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Mechanistically, osteocalcin signaling has been linked to the G proteincoupled receptor GPRC6A, providing a plausible pathway through which bone-derived signals influence pancreatic -cells, adipocytes, and Leydig cells

Topical application of a glutathione amino acid precursor formulation to ex vivo skin samples prior to UVB irradiation led to a significant suppression of cyclobutene pyrimidine dimers (CPD), markers of DNA damage

hazard ratio 0.70, 95% confidence interval 0.49 to 0.99) compared with the use of GLP-1 receptor agonists after a median follow-up time of 9.0 months